Daptomycin Associated Rhabdomyolysis with Concurrent Use of Atorvastatin

The Concomitant Use of Atorvastatin and Amlodipine Leading to Rhabdomyolysis

A 65-year-old man, with a history of hypertension and hyperlipidemia, presented with intractable lower back pain, shortness of breath, and decreasing urine output at the emergency room and was admitted after he was found to have elevated creatinine kinase levels of greater than 160,000 U/L. We discontinued all his home medications, which included atorvastatin and amlodipine. We trended his crea...

Neutropenia associated with prolonged daptomycin use.

TO THE EDITOR—Daptomycin is increasingly used for treatment of staphylococcal infections including methicillin-resistant Staphylococcus aureus (MRSA). We report a case of neutropenia as an adverse effect of long-term daptomycin therapy.

Atorvastatin Use Associated With Acute Pancreatitis

Few data are present in the literature on the relationship between atorvastatin use and acute pancreatitis. The aim of this study was to explore this issue in Taiwan. Using representative claims data established from the Taiwan National Health Insurance Program, this case-control study consisted of 5810 cases aged 20 to 84 years with a first-time diagnosis of acute pancreatitis during the perio...

Rhabdomyolysis with simvastatin use.

Severe rhabdomyolysis associated with catha edulis(khat) use

Severe rhabdomyolysis is a rare complication of exposure to the recreational drug khat. Adverse reactions to khat that have been reported in the literature include myocardial infarction and reversible vasoconstriction syndrome. The active ingredient, cathinone, is a naturally occurring beta-ketone amphetamine that may be responsible for this severe catecholaminergic response. Here we report a c...